|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Axin Signaling Complex
|
|
Descriptor Spanish:
|
|
Complejo de Señalización de la Axina
|
|
Descriptor Portuguese:
|
|
Complexo de Sinalização da Axina
|
|
Synonyms English:
|
|
Axin Signaling Complex Proteins
Destruction Complex, beta-Catenin
Signaling Complex, Axin
beta Catenin Destruction Complex
beta-Catenin Destruction Complex
|
|
Tree Number:
|
|
D05.500.117
D12.776.476.081
|
|
Definition English:
|
|
A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription. |
|
History Note English:
|
|
2012
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
54555
|
|
Unique Identifier:
|
|
D060465
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS
|